Researcher profile

William T. Friedewald

· Lung Institute

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Publications

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Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
1972 · Clinical Chemistry · DOI 10.1093/clinchem/18.6.499

Abstract A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.

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Co-authors

Robert I. Levy

Lung Institute

1 shared publication
Donald S. Fredrickson

Lung Institute

1 shared publication