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William T. Friedewald

· Lung Institute

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William T. Friedewald is a registered researcher in their academic field.

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Diabetes, Cardiovascular Risks, and Lipoproteins, Lipoproteins and Cardiovascular Health, Cancer, Lipids, and Metabolism · 1972 · Clinical Chemistry

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

William T. Friedewald, Robert I. Levy, Donald S. Fredrickson

Abstract A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.

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