Advanced Techniques in Biology & Medicine
The present study was out to evaluate the antibacterial activity of crude ethanolic extract of Cocos nucifera (coconut) husk ash against some pathogenic bacteria (Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli) and their wound healing potential in experimental rats. The wound healing potential of the ethanolic extract ointment of Cocos nucifera (coconut) husk ash was evaluated in albino rats using excision wound model. Eighteen rats were divided into three groups of six each. Group 1 received no treatment (blank ointment base) which is the negative control, Group II received treatment with 1% silver sulphadiazine and group III received treatment with coconut husk ash extract. 1% silver sulphadiazine ointment was used as standard for the activity comparison. Wound healing was monitored on day 4, 8, 12 and 16. Wound healing parameters such as percentage of wound contraction rate and epithelialization period were observed.