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2009 · Chemical Society Reviews

The chemistry of graphene oxide

Daniel R. Dreyer, Sungjin Park, Christopher W. Bielawski, Rodney S. Ruoff

The chemistry of graphene oxide is discussed in this critical review. Particular emphasis is directed toward the synthesis of graphene oxide, as well as its structure. Graphene oxide as a substrate for a variety of chemical transformations, including its reduction to graphene-like materials, is also discussed. This review will be of value to synthetic chemists interested in this emerging field of materials science, as well as those investigating applications of graphene who would find a more thorough treatment of the chemistry of graphene oxide useful in understanding the scope and limitations of current approaches which utilize this material (91 references).

11,492 citations2 views
DOI: 10.1039/b917103g
2007 · Chemical Society Reviews

Fluorine in medicinal chemistry

Sophie Purser, Peter R. Moore, Steve Swallow, Véronique Gouverneur

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.

7,501 citations0 views
DOI: 10.1039/b610213c