TY  - JOUR
TI  - Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study
AU  - Ami D. Sperber
AU  - Shrikant I. Bangdiwala
AU  - Douglas A. Drossman
AU  - Uday C. Ghoshal
AU  - Magnus Simrén
AU  - Jan Tack
AU  - William E. Whitehead
AU  - Dan L. Dumitraşcu
AU  - Xuicai Fang
AU  - Shin Fukudo
AU  - John Kellow
AU  - Edith Okeke
AU  - Eamonn M.M. Quigley
AU  - Max J. Schmulson
AU  - Peter J. Whorwell
AU  - Timothy Archampong
AU  - Payman Adibi
AU  - Viola Andresen
AU  - Marc A. Benninga
AU  - Bruno Bonaz
AU  - Serhat Bor
AU  - Luis Bustos Fernández
AU  - Suck Chei Choi
AU  - Enrico Corazziari
AU  - Carlos Fernando de Magalhães Francisconi
AU  - Albis Hani
AU  - Л. Б. Лазебник
AU  - Yeong Yeh Lee
AU  - Agata Mulak
AU  - M. Masudur Rahman
AU  - Javier Santos
AU  - Mashiko Setshedi
AU  - Ari Fahrial Syam
AU  - Stephen Vanner
AU  - Reuben K. Wong
AU  - Aurelio López‐Colombo
AU  - Valeria Atenea Costa
AU  - Ram Dickman
AU  - Motoyori Kanazawa
AU  - Ammar Hassanzadeh Keshteli
AU  - Rutaba Khatun
AU  - Iradj Maleki
AU  - Pierre Poitras
AU  - Nitesh Pratap
AU  - O. V. Stefanyuk
AU  - S R Thomson
AU  - Judith Zeevenhooven
AU  - Olafur S. Palsson
PY  - 2020
JO  - Gastroenterology
DO  - 10.1053/j.gastro.2020.04.014
UR  - https://doi.org/10.1053/j.gastro.2020.04.014
AB  - BACKGROUND & AIMS: Although functional gastrointestinal disorders (FGIDs), now called disorders of gut-brain interaction, have major economic effects on health care systems and adversely affect quality of life, little is known about their global prevalence and distribution. We investigated the prevalence of and factors associated with 22 FGIDs, in 33 countries on 6 continents. METHODS: Data were collected via the Internet in 24 countries, personal interviews in 7 countries, and both in 2 countries, using the Rome IV diagnostic questionnaire, Rome III irritable bowel syndrome questions, and 80 items to identify variables associated with FGIDs. Data collection methods differed for Internet and household groups, so data analyses were conducted and reported separately. RESULTS: Among the 73,076 adult respondents (49.5% women), diagnostic criteria were met for at least 1 FGID by 40.3% persons who completed the Internet surveys (95% confidence interval [CI], 39.9-40.7) and 20.7% of persons who completed the household surveys (95% CI, 20.2-21.3). FGIDs were more prevalent among women than men, based on responses to the Internet survey (odds ratio, 1.7; 95% CI, 1.6-1.7) and household survey (odds ratio, 1.3; 95% CI, 1.3-1.4). FGIDs were associated with lower quality of life and more frequent doctor visits. Proportions of subjects with irritable bowel syndrome were lower when the Rome IV criteria were used, compared with the Rome III criteria, in the Internet survey (4.1% vs 10.1%) and household survey (1.5% vs 3.5%). CONCLUSIONS: In a large-scale multinational study, we found that more than 40% of persons worldwide have FGIDs, which affect quality of life and health care use. Although the absolute prevalence was higher among Internet respondents, similar trends and relative distributions were found in people who completed Internet vs personal interviews.
ER  -