MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of systematic changes across experimental conditions. Small repli…

Protein Phase Separation: A New Phase in Cell Biology

The Emergence of lncRNAs in Cancer Biology

Abstract The discovery of numerous noncoding RNA (ncRNA) transcripts in species from yeast to mammals has dramatically altered our understanding of cell biology, especially the biology of diseases such as cancer. In hum…