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Research institution

University of Lagos

NG

10 researchers0 verified7 linked papers307 indexed citations

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Public research profiles associated with University of Lagos.

Research from this institution

Publications linked through researcher authorship records.

2012 · PLoS ONE · 97 citations

Pre-Vaccination Nasopharyngeal Pneumococcal Carriage in a Nigerian Population: Epidemiology and Population Biology

BACKGROUND: Introduction of pneumococcal vaccines in Nigeria is a priority as part of the Accelerated Vaccine Introduction Initiative (AVI) of the Global Alliance for Vaccines and Immunisation (GAVI). However, country data on the burden of pneumococcal disease (IPD) is limited and coverage by available conjugate vaccines is unknown. This study was carried out to describe the pre vaccination epidemiology and population biology of pneumococcal carriage in Nigeria. METHODS: This was a cross sectional survey. Nasopharyngeal swabs (NPS) were obtained from a population sample in 14 contiguous peri-urban Nigerian communities. Data on demographic characteristics and risk factor for carriage were obtained from all study participants. Pneumococci isolated from NPS were characterised by serotyping, antimicrobial susceptibility and Multi Locus Sequencing Typing (MLST). RESULTS: The prevalence of pneumococcal carriage was 52.5%. Carriage was higher in children compared to adults (67.4% vs. 26%), highest (≈90%) in infants aged

1972 · Journal of Fish Biology · 69 citations

The biology of the West African shad <i>Ethmalosa fimbriata (Bowdich)</i> in the Lagos Lagoon, Nigeria

The biology of the population of Ethmalosa fimbriata occurring in the Lagos lagoon was investigated. Three size groups, 35–69 mm (Yoyo), 70–169 mm (Efolo) and 170 mm and above (Agbodo) occur in the lagoon and the spatial distribution of these size groups and the length frequency distribution of the species is given. The relationship between length, weight, age and growth is discussed and the food and feeding intra‐relationship of the size groups is shown. Information on the fecundity and possible spawning periods is discussed.

2012 · 38 citations

The effect of concept mapping instructional strategy on the biology achievement of senior secondary school slow learners

The study investigated the comparative effectiveness of the expository and concept mapping instructional strategy of presenting secondary school biology concepts to slow learners. One hundred and twenty four biology slow learners were identified and randomly assigned to the expository group (n=62) and concept mapping group (n=62) and respectively taught the concept of photosynthesis. The groups were post-tested after two weeks of teaching for any significant differences in their biology achievement. Analysis of post-test scores indicated that the group taught by the concept mapping instructional strategy performed significantly (p&amp;lt;0.05) better than their expository group counterparts. Specifically, female slow learners taught with the concept mapping instructional strategy performed significantly (p&amp;lt;0.05) better than their male counterparts taught by the same method. These results have implications for biology teacher preparation, especially in the areas of teaching females and identifying slow learners and adopting effective methods of tackling their problems

2021 · Bioinformatics and Biology Insights · 28 citations

Anticancer Potential of <i>Moringa oleifera</i> on BRCA-1 Gene: Systems Biology

Breast cancer has consistently been a global challenge that is prevalent among women. There is a continuous increase in the high number of women mortality rates because of breast cancer and affecting nations at all modernization levels. Women with high-risk factors, including hereditary, obesity, and menopause, have the possibility of developing breast cancer growth. With the advent of radiotherapy, chemotherapy, hormone therapy, and surgery in breast cancer treatment, breast cancer survivors have increased. Also, the design and development of drugs targeting therapeutic enzymes effectively treat the tumour cells early. However, long-term use of anticancer drugs has been linked to severe side effects. This research aims to develop potential drug candidates from Moringa oleifera, which could serve as anticancer agents. In silico analysis using Schrödinger Molecular Drug Discovery Suite and SWISS ADME was employed to determine the therapeutic potential of phytochemicals from M oleifera against breast cancer via molecular docking, pharmacokinetic parameters, and drug-like properties. The result shows that rutin, vicenin-2, and quercetin-3-O-glucoside have the highest binding energy of −7.522, −6.808, and −6.635 kcal/mol, respectively, in the active site of BRCA-1. The essential amino acids involved in the protein-ligand interaction following active site analysis are ASN 1678, ASN 1774, GLY 1656, LEU 1657, GLN 1779, LYS 1702, SER 1655, PHE 1662, ARG 1699, GLU 1698, and VAL 1654. Thus, we propose that bioactive compounds from M oleifera may be potential novel drug candidates in the treatment of breast cancer.

2017 · Journal of Education and Training Studies · 25 citations

Gender Inequality and Role-strained among Male Nursing Students in Selected Nursing Institution, Lagos, Nigeria

Gender discrimination remains problem in the world as a whole and unfortunately, nursing profession is not immune to this problem. Gender discrimination is rejection or restriction made on the basis of socially constructed gender roles which prevents a person from relishing full human rights. Role strain has been defined as when an individual is likely to experience tension in coping with the rations of dissenting roles. Role strain can occur when the men in nursing are observed by lecturers and peers to occupy a female role distinct with their masculine gender which may lead to diminishment of their individual contribution. Simple random sampling method was used to select nursing institutions that was included in the study and convenience sampling method was used to select the respondents that partook in the study. The study population is male nursing students from 200 level-500 level of the selected nursing institutions. A questionnaire including measures of gender role identity and perceived gender relevance of careers was administered to 205 male student nurses from three nursing institutions. The results showed that 32% of the respondents had not experienced gender bias during nursing school, whereas 68% reported gender bias from the lecturers and the nursing staff. This study has implications for nursing profession that address the current predicament in the nursing field caused by discrimination and social isolation that man face. Therefore, Nursing and Midwifery council of Nigeria should develop a strategic plan to addresses the eradication of discrimination and racism in and by the nursing profession.

1997 · International Journal of Geriatric Psychiatry · 25 citations

Psychiatric disorders in Nigerian nursing home residents

BACKGROUND: The prevalence of psychiatric disorders in nursing homes, which has not been studied before in Nigeria, is the subject of this cross-sectional study. METHOD: Psychiatric disorders were assessed in 23 of the 29 residents of the two nursing homes in Lagos and diagnoses based on DSM-III-R criteria (APA, 1987) and AGECAT (Copeland et al., 1986) were made independently. RESULTS: The commonest diagnoses were dementia in 11 out of 23 residents and depression in four residents. Overall prevalence rate of psychiatric disorders was 74%. CONCLUSION: The present prevalence rate of psychiatric disorders is similar to those reported in similar institutions in the industrialized societies. This has implications for the care of the elderly in a non-industrialized society.

1968 · Journal of Economic Entomology · 25 citations

The Biology and Ecology of Busseola fusea and Sesamia Species in South-Western Nigeria. I. Distribution and Population Studies

The distribution of maize stem borers, Busseola fusca Fuller, Sesamia calamistis Hampson, and S. penniseti Bowden, throughout south-western Nigeria was studied between November and December 1964. The maize-sample survey revealed that B. fusca was more abundant than S. calamistis. While B. fusca was prevalent in the southerly, more humid lowland rainforest zones, S. calamistis was generally distributed and was more prevalent in the dry savanna zones of the region. S. penniseti was not abundant and was very sparsely distributed. There was a marked difference in the position of egg masses on the maize plants. All egg masses of B. fusca were laid within 30 inches of the maize whorl, while S. calamistis egg masses were spread over greater distances from the whorl. This distribution appears to be associated with the larval habits of both B. fusea and S. calamistis. Larval populations studies revealed that in lbadan (and probably south-western Nigeria) there are 4 generations of B. fusca in maize per annum. There are 2 generations between April and July, 1 in September-October, and another in November. It is the larvae of the November generation which go into the dry-season diapause and which later give rise to the 1st-generation adults the following year. S. calamistis,, although not so numerous as B. fusca, was observed to breed throughout the year.